Products

anti- CHMP1B antibody

FNab01657 Catalogue No.
Synonyms
C18orf2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Isotype
IgG
Tested Application
ELISA, WB, IHC
Product Information
Product Name
anti- CHMP1B antibody
Catalogue No.
FNab01657
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III) , a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs) . Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010) , is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]) .
Immunogen Information
Immunogen
chromatin modifying protein 1B
Synonyms
C18orf2
Observed MW
30 kDa
Application
Tested Application
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Uniprot information
UniProt ID
Q7LBR1
Images
Immunohistochemistry of paraffin-embedded mouse kidney using FNab01657 (CHMP1B antibody) at dilution of 1:50
HeLa cells were subjected to SDS PAGE followed by western blot with FNab01657 (CHMP1B antibody) at dilution of 1:1000