CDC23 antibody

Synonyms:ANAPC8 antibody, APC8 antibody, CDC23 antibody, Cyclosome subunit 8 antibody
Catalogue No.:FNab01520Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
CDC23 antibody
Catalogue No.
FNab01520
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
cell division cycle 23 homolog
Alternative Names
ANAPC8 antibody, APC8 antibody, CDC23 antibody, Cyclosome subunit 8 antibody
UniProt ID
Q9UJX2
Observed MW
49 kDa
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:200-1:2000
Validated Images
K-562 cells were subjected to SDS PAGE followed by western blot with FNab01520(CDC23 Antibody) at dilution of 1:500
Background
Component of the anaphase promoting complex/cyclosome(APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'-and 'Lys-63'-linked polyubiquitin chains.