Products
CD39 antibody
- Product Name
- CD39 antibody
- Catalogue No.
- FNab01474
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ectonucleoside triphosphate diphosphohydrolase 1
- Alternative Names
- ATPDase antibody, CD39 antibody, DKFZp686D194 antibody, DKFZp686I093 antibody, Ecto apyrase antibody, Ecto ATP diphosphohydrolase 1 antibody, Ecto ATPase 1 antibody, Ecto ATPDase 1 antibody, ENTPD1 antibody, FLJ40921 antibody, FLJ40959 antibody, NTPDase 1 antibody
- UniProt ID
- P49961
- Observed MW
- 75-95 kDa
Application
- Tested Applications
- ELISA, WB, IHC, FC, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab01474(ENTPD1 antibody) at dilution of 1:500
IP Result of anti-ENTPD1 (IP:FNab01474, 4ug; Detection:FNab01474 1:800) with mouse liver tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human tonsillitis using FNab01474(ENTPD1 antibody) at dilution of 1:50
- Background
- ENTPD1(Ectonucleoside triphosphate diphosphohydrolase 1) is also named as CD39, NTPDase 1, Ecto-ATPDase 1 and belongs to the GDA1/CD39 NTPase family. In the nervous system, it can hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission.It is a noncovalent tetrameric protein and that detergent inhibition of enzymatic activity is caused by dissociation of ectoapyrase tetramers into monomers(PMID: 9733785).And it is a 70-to 100-kDa protein that is heavily N-glycosylated(PMID:7930580). It has 3 isoforms produced by alternative splicing. CD39 preferentially occurred as a dimer that could be dissociated into monomeric forms.(PMID: 12694193). The soluble isoform of CD39(38-478 amino acid) locates to the extracellular part and FNab01474 recognizes both the 3 isoforms and soluble form of CD39(38-478aa) molecule.
