Products
Cd2ap antibody
- Product Name
- Cd2ap antibody
- Catalogue No.
- FNab01455
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- CD2-associated protein
- UniProt ID
- Q9Y5K6
- Observed MW
- 70 kDa
Application
- Tested Applications
- ELISA, WB, IF, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:500-1:1000; IF: 1:10-1:100
Validated Images
mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab01455(Cd2ap antibody) at dilution of 1:2000
IP Result of anti-Cd2ap (IP:FNab01455, 4ug; Detection:FNab01455 1:2000) with mouse brain tissue lysate 2560ug.
- Background
- Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis.
