Products
Caveolin-1 antibody
- Product Name
- Caveolin-1 antibody
- Catalogue No.
- FNab01314
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 0H8
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- caveolin 1, caveolae protein, 22kDa
- Alternative Names
- caveolin 1 antibody, CAV1 antibody
- UniProt ID
- Q03135
- Observed MW
- 22 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
PC-3 cells were subjected to SDS PAGE followed by western blot with FNab01314(CAV1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human lung cancer using FNab01314(CAV1 antibody) at dilution of 1:50
- Background
- Caveolin-1 is a protein that in humans is encoded by the CAV1 gene.The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene.
