Catalase-Specific antibody

Catalogue No.:FNab01302Reactivity:Human
Host:RabbitTested Application:ELISA, WB, IF, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
Catalase-Specific antibody
Catalogue No.
FNab01302
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
catalase
UniProt ID
P04040
Observed MW
60kd
Application
Tested Applications
ELISA, WB, IF, IHC
Recommended dilution
WB: 1:1000-1:4000; IHC: 1:20-1:200; IF: 1:10-1:100
Validated Images
HT-1080 cells were subjected to SDS PAGE followed by western blot with FNab01302(CAT-Specific antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human hepatocirrhosis using FNab01302(CAT-Specific antibody) at dilution of 1:100
Background
CAT(Catalase) belongs to the catalase family. It is involved in catabolic pathway of activated oxygen species and free radical detoxification and the catalase overexpression has a protective role against UVB irradiation by preventing DNA damage mediated by the late ROS increase. Mammalian catalase of approximately 240 kD occurs as a complex of 4 identical subunits, each of which contains 526 amino acid residues(PMID:19122680). Defects in CAT are the cause of acatalasemia(ACATLAS). This antibody is specific to CAT.