Products
Caspase 2 antibody
- Product Name
- Caspase 2 antibody
- Catalogue No.
- FNab01287
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- caspase 2, apoptosis-related cysteine peptidase
- Alternative Names
- CASP 2 antibody, CASP2 antibody, Caspase 2 antibody, ICH 1L antibody, ICH 1L/1S antibody, ICH1 antibody, NEDD 2 antibody, NEDD2 antibody, Protease ICH 1 antibody
- UniProt ID
- P42575
- Observed MW
- 50 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:50-1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab01287(CASP2 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human gastric cancer tissue slide using FNab01287(Caspase 2 Antibody) at dilution of 1:100
- Background
- This gene encodes a member of the cysteine-aspartic acid protease(caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
