CAPZB antibody

Catalogue No.:FNab01259Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
CAPZB antibody
Catalogue No.
FNab01259
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
capping protein(actin filament) muscle Z-line, beta
UniProt ID
P47756
Observed MW
30-31 kDa
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:500-1:2000
Validated Images
Hela cells were subjected to SDS PAGE followed by western blot with FNab01259(CAPZB antibody) at dilution of 1:3000
Background
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments(barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins(such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization.