Products
C4BPB antibody
- Product Name
- C4BPB antibody
- Catalogue No.
- FNab01114
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- complement component 4 binding protein, beta
- Alternative Names
- C4b binding protein beta chain antibody, C4BP antibody, C4BPB antibody
- UniProt ID
- P20851
- Observed MW
- 40-45 kDa
Application
- Tested Applications
- ELISA, IHC, WB, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:100
Validated Images
Various lysates were subjected to SDS PAGE followed by western blot with FNab01114(C4BPB antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse kidney using FNab01114(C4BPB antibody) at dilution of 1:100
- Background
- This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.
