C4BPA antibody

Synonyms:C4BP antibody
Catalogue No.:FNab01113Reactivity:Human
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
C4BPA antibody
Catalogue No.
FNab01113
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
complement component 4 binding protein, alpha
Alternative Names
C4BP antibody
UniProt ID
P04003
Observed MW
70 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
human blood tissue were subjected to SDS PAGE followed by western blot with FNab01113(C4BPA Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab01113(C4BPA Antibody) at dilution of 1:50
Background
Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator(C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex(C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component.