human brain tissue were subjected to SDS PAGE followed by western blot with FNab00947(BRD3 antibody) at dilution of 1:200
IP Result of anti-BRD3 (IP:FNab00947, 4ug; Detection:FNab00947 1:500) with HeLa cells lysate 4000ug.
Immunohistochemistry of paraffin-embedded human ovary tumor using FNab00947(BRD3 antibody) at dilution of 1:50
Background
Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling and interaction with transcription factors. Regulates transcription by promoting the binding of the transcription factor GATA1 to its targets(By similarity). Regulates transcription of the CCND1 gene.