mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab00886( BHLHA15 Antibody) at dilution of 1:300
IP Result of anti-BHLHA15 (IP:FNab00886, 3ug; Detection:FNab00886 1:300) with mouse liver tissue lysate 6800ug.
Background
Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'(By similarity).