BHLHA15 antibody

Synonyms:BHLHB8 antibody, MIST1 antibody
Catalogue No.:FNab00886Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
BHLHA15 antibody
Catalogue No.
FNab00886
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
basic helix-loop-helix family, member a15
Alternative Names
BHLHB8 antibody, MIST1 antibody
UniProt ID
Q7RTS1
Observed MW
30 kDa
Application
Tested Applications
ELISA, WB, IP
Recommended dilution
WB: 1:500-1:2000; IP: 1:500-1:1000
Validated Images
mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab00886( BHLHA15 Antibody) at dilution of 1:300
IP Result of anti-BHLHA15 (IP:FNab00886, 3ug; Detection:FNab00886 1:300) with mouse liver tissue lysate 6800ug.
Background
Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'(By similarity).