BCL10 antibody

Synonyms:BCL10 antibody, Cellular homolog of vCARMEN antibody, CLAP antibody, CARMEN antibody, CARD like apoptotic protein antibody
Catalogue No.:FNab00836Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
BCL10 antibody
Catalogue No.
FNab00836
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
B-cell CLL/lymphoma 10
Alternative Names
BCL10 antibody, Cellular homolog of vCARMEN antibody, CLAP antibody, CARMEN antibody, CARD like apoptotic protein antibody
UniProt ID
O95999
Observed MW
32kd
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:1000; IHC: 1:20-1:200
Validated Images
Mouse ovary tissue were subjected to SDS PAGE followed by western blot with FNab00836(BCL10 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human lung cancer using FNab00836(BCL10 antibody) at dilution of 1:100
Background
Involved in adaptive immune response(PubMed:25365219). Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1(PubMed:18264101).