band 3 antibody

Synonyms:AE 1 antibody, AE1 antibody, Anion exchange protein 1 antibody, Anion exchanger 1 antibody, band 3 antibody, Band 3 anion transport protein antibody, BND3 antibody, CD233 antibody, DI antibody, EMPB3 antibody, EPB3 antibody, FR antibody, RTA1A antibody, SLC4A1 antibody, SW antibody, WD antibody, WD1 antibody, WR antibody
Catalogue No.:FNab00798Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, IHC, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
band 3 antibody
Catalogue No.
FNab00798
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
solute carrier family 4, anion exchanger, member 1
Alternative Names
AE 1 antibody, AE1 antibody, Anion exchange protein 1 antibody, Anion exchanger 1 antibody, band 3 antibody, Band 3 anion transport protein antibody, BND3 antibody, CD233 antibody, DI antibody, EMPB3 antibody, EPB3 antibody, FR antibody, RTA1A antibody, SLC4A1 antibody, SW antibody, WD antibody, WD1 antibody, WR antibody
UniProt ID
P02730
Observed MW
43 kDa,52-70 kDa,95-102 kDa
Application
Tested Applications
ELISA, IHC, WB
Recommended dilution
WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
Various lysates were subjected to SDS PAGE followed by western blot with FNab00798(SLC4A1 Antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human spleen using FNab00798(SLC4A1 antibody) at dilution of 1:50
Background
Anion exchanger 1 (AE1), also known as band 3, is a 95-100 kDa transmembrane glycoprotein which is abundantly expressed in erythrocyte plasma membrane and mediates the electroneutral exchange of Cl- and HCO3-. It contains a 52-55 kDa C-terminal membrane crossing domain and a 43 kDa N-terminal cytoplasmic domain. Degradation of band 3 protein occurred during erythrocyte aging. The oxidative stress can also activate the proteolysis of band 3 through caspases.