mouse lung tissue were subjected to SDS PAGE followed by western blot with FNab00769(B3GNT5 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human lung using FNab00769(B3GNT5 antibody) at dilution of 1:50
Background
Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto-or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide(LacCer) and neolactotetraosylceramide(nLc(4)Cer; paragloboside), resulting in the synthesis of Lc(3)Cer and neolactopentaosylceramide(nLc(5)Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development.