B3GNT5 antibody

Catalogue No.:FNab00769Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
B3GNT5 antibody
Catalogue No.
FNab00769
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
UniProt ID
Q9BYG0
Observed MW
44kd
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
mouse lung tissue were subjected to SDS PAGE followed by western blot with FNab00769(B3GNT5 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human lung using FNab00769(B3GNT5 antibody) at dilution of 1:50
Background
Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto-or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide(LacCer) and neolactotetraosylceramide(nLc(4)Cer; paragloboside), resulting in the synthesis of Lc(3)Cer and neolactopentaosylceramide(nLc(5)Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development.