HepG2 cells were subjected to SDS PAGE followed by western blot with FNab00758(AZI2 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach tissue slide using FNab00758(AZI2 Antibody) at dilution of 1:50
Background
Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1.