Products
ASZ1 antibody
- Product Name
- ASZ1 antibody
- Catalogue No.
- FNab00653
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ankyrin repeat, SAM and basic leucine zipper domain containing 1
- Alternative Names
- ALP1 antibody, ANKL1 antibody, Ankyrin like protein 1 antibody, ASZ1 antibody, C7orf7 antibody, GASZ antibody, Orf3 antibody
- UniProt ID
- Q8WWH4
- Observed MW
- 48-50kd
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:2000
Validated Images
mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab00653(ASZ1 antibody) at dilution of 1:500
- Background
- Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation(By similarity).
