ASTL antibody

Synonyms:ASTL antibody, Oocyte astacin antibody, Ovastacin antibody, SAS1B antibody
Catalogue No.:FNab00651Reactivity:Human
Host:RabbitTested Application:ELISA, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
ASTL antibody
Catalogue No.
FNab00651
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
astacin-like metallo-endopeptidase(M12 family)
Alternative Names
ASTL antibody, Oocyte astacin antibody, Ovastacin antibody, SAS1B antibody
UniProt ID
Q6HA08
Observed MW
46 kDa
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:500-1:1000
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00651( ASTL Antibody) at dilution of 1:500
Background
Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding(By similarity).