Products
ASK1 antibody
- Product Name
- ASK1 antibody
- Catalogue No.
- FNab00640
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- mitogen-activated protein kinase kinase kinase 5
- Alternative Names
- ASK 1 antibody, ASK1 antibody, MAP3K5 antibody, MAPK/ERK kinase kinase 5 antibody, MAPKKK5 antibody, MEK kinase 5 antibody, MEKK 5 antibody, MEKK5 antibody
- UniProt ID
- Q99683
- Observed MW
- 155 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:100-1:1000
Validated Images
Raji cells were subjected to SDS PAGE followed by western blot with FNab00640(ASK1 antibody) at dilution of 1:500
- Background
- ASK1(Apoptosis signal-regulating kinase 1) is also named as MAP3K5, MAPKKK5, MEKK5 and belongs to the MAP kinase kinase kinase subfamily. It is an evolutionarily conserved mitogen activated protein 3-kinase that activates both Jnk and p38 mitogen-activated protein kinases. ASK1 is is activated in response to various cytotoxic stresses including TNF, Fas and reactive oxygen species(ROS) such as H2O2, and activates c-Jun NH 2-terminal kinase(JNK) and p38.
