HeLa cells were subjected to SDS PAGE followed by western blot with FNab00631(ASF1A antibody) at dilution of 1:600
IP Result of anti-ASF1A (IP:FNab00631, 4ug; Detection:FNab00631 1:800) with HEK-293 cells lysate 2800ug.
Immunohistochemistry of paraffin-embedded human lymphoma using FNab00631(ASF1A antibody) at dilution of 1:10
Background
Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1(CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci(SAHF) and efficient senescence-associated cell cycle exit.