Products
ARHGEF7 antibody
- Product Name
- ARHGEF7 antibody
- Catalogue No.
- FNab00564
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Rho guanine nucleotide exchange factor(GEF) 7
- Alternative Names
- COOL1 antibody, KIAA0142 antibody, P85SPR antibody, PAK3BP antibody, PIXB antibody
- UniProt ID
- Q14155
- Observed MW
- 70 kDa
Application
- Tested Applications
- ELISA, IP, WB
- Recommended dilution
- WB: 1:1000-1:4000; IP: 1:500-1:2000
Validated Images
PC-12 cells were subjected to SDS PAGE followed by western blot with FNab00564 (ARHGEF7 antibody) at dilution of 1:2000
IP Result of anti-ARHGEF7 (IP:FNab00564, 4ug; Detection:FNab00564 1:1000) with HeLa cells lysate 1200ug.
- Background
- Acts as a RAC1 guanine nucleotide exchange factor(GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions(By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.
