Products
ARHGAP10 antibody
- Product Name
- ARHGAP10 antibody
- Catalogue No.
- FNab00546
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Rho GTPase activating protein 10
- Alternative Names
- GRAF2 antibody
- UniProt ID
- A1A4S6
- Observed MW
- 89 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab00546(ARHGAP10 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human heart tissue slide using FNab00546(ARHGAP10 Antibody) at dilution of 1:200
- Background
- GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death(By similarity).
