Products
ARAP3 antibody
- Product Name
- ARAP3 antibody
- Catalogue No.
- FNab00523
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
- Alternative Names
- CENTD3 antibody
- UniProt ID
- Q8WWN8
- Observed MW
- 45 kDa
Application
- Tested Applications
- ELISA, IHC
- Recommended dilution
- IHC: 1:20-1:200
Validated Images
Immunohistochemistry of paraffin-embedded human colon tissue slide using FNab00523(ARAP3 Antibody) at dilution of 1:50
- Background
- Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate(PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate(PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Acts on ARF6, RAC1, RHOA and CDC42. Plays a role in the internalization of anthrax toxin.
