AQR antibody

Synonyms:KIAA0560 antibody
Catalogue No.:FNab00520Reactivity:Human
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
AQR antibody
Catalogue No.
FNab00520
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
aquarius homolog(Mouse)
Alternative Names
KIAA0560 antibody
UniProt ID
O60306
Observed MW
160 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00520(AQR Antibody) at dilution of 1:1500
Immunohistochemistry of paraffin-embedded human brain slide using FNab00520(AQR Antibody) at dilution of 1:50
Background
Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP(small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns(40 nucleotides upstream of the branchpoint) during the late stages of splicing.