Products
APLF antibody
- Product Name
- APLF antibody
- Catalogue No.
- FNab00484
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- aprataxin and PNKP like factor
- Alternative Names
- Aprataxin and PNK-like factor|Apurinic-apyrimidinic endonuclease APLF|PNK and APTX-like FHA domain-containing protein|XRCC1-interacting protein 1|APLF|C2orf13|PALF|XIP1 antibody
- UniProt ID
- Q8IW19
- Observed MW
- 60 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500 - 1:2000
Validated Images
PC-3 cells were subjected to SDS PAGE followed by western blot with FNab00484(APLF antibody) at dilution of 1:600
- Background
- Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic(AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage.
