anti- APLF antibody
FNab00484
Catalogue No.
- Synonyms:
- C2orf13, PALF, XIP1
- Host:
- Rabbit
- Reactivity:
- Human
- Isotype:
- IgG
- Tested Application:
- ELISA, WB
Product Information
- Product Name
- anti- APLF antibody
- Catalogue No.
- FNab00484
- Size
- 100µg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Host
- Rabbit
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
- Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic(AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage.
Immunogen Information
- Immunogen
- aprataxin and PNKP like factor
- Synonyms
- C2orf13, PALF, XIP1
- Observed MW
- 60 kD
Application
- Tested Application
- ELISA, WB
- Recommended dilution
- WB: 1:500 - 1:2000
Uniprot information
- UniProt ID
- Q8IW19
Images
- Image 4
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PC-3 cells were subjected to SDS PAGE followed by western blot with FNab00484(APLF antibody) at dilution of 1:600