Products
APH1A antibody
- Product Name
- APH1A antibody
- Catalogue No.
- FNab00481
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- anterior pharynx defective 1 homolog A
- Alternative Names
- APH 1A antibody, Aph 1alpha antibody, APH1A antibody, CGI 78 antibody, Gamma secretase subunit APH 1A antibody, PSF antibody, UNQ579/PRO1141 antibody
- UniProt ID
- Q96BI3
- Observed MW
- 30 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500 - 1:1000
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab00481(APH1A antibody) at dilution of 1:500
- Background
- Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP(beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.
