Products
AP3B2 antibody
- Product Name
- AP3B2 antibody
- Catalogue No.
- FNab00464
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- adaptor-related protein complex 3, beta 2 subunit
- Alternative Names
- AP 3 complex subunit beta 2 antibody, AP3B2 antibody, Beta 3B adaptin antibody, DKFZp686D17136 antibody, NAPTB antibody
- UniProt ID
- Q13367
- Observed MW
- 120-140 kDa
Application
- Tested Applications
- ELISA, WB,IP
- Recommended dilution
- WB: 1:200-1:2000IP: 1:200-1:2000
Validated Images
rat brain tissue were subjected to SDS PAGE followed by western blot with FNab00464(AP3B2 Antibody) at dilution of 1:600
IP Result of anti-AP3B2 (IP:FNab00464, 4ug; Detection:FNab00464 1:500) with mouse brain tissue lysate 3600ug.
- Background
- Subunit of non-clathrin-and clathrin-associated adaptor protein complex 3(AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network(TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
