Products
AP3B1 antibody
- Product Name
- AP3B1 antibody
- Catalogue No.
- FNab00463
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- adaptor-related protein complex 3, beta 1 subunit
- Alternative Names
- ADTB3 antibody, ADTB3A antibody, AP 3 complex subunit beta 1 antibody, AP3B1 antibody, Beta 3A adaptin antibody, HPS antibody, HPS2 antibody, PE antibody
- UniProt ID
- O00203
- Observed MW
- 140 kDa
Application
- Tested Applications
- ELISA, WB, IF, IP
- Recommended dilution
- WB: 1:500-1:5000IP: 1:200-1:2000
Validated Images
mouse thymus tissue were subjected to SDS PAGE followed by western blot with FNab00463(AP3B1 antibody) at dilution of 1:500
IP Result of anti-AP3B1 (IP:FNab00463, 3ug; Detection:FNab00463 1:500) with COLO 320 cells lysate 2500ug.
- Background
- Subunit of non-clathrin-and clathrin-associated adaptor protein complex 3(AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network(TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
