Products
ANO2 antibody
- Product Name
- ANO2 antibody
- Catalogue No.
- FNab00442
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- anoctamin 2
- Alternative Names
- ANO2 antibody, anoctamin 2 antibody, C12orf3 antibody, DKFZp434P102 antibody, TMEM16B antibody, Transmembrane protein 16B antibody
- UniProt ID
- Q9NQ90
- Observed MW
- 114 kDa
Application
- Tested Applications
- ELISA, WB, IF, IP, IHC
- Recommended dilution
- WB: 1:1000-1:10000; IHC: 1:20-1:200; IF: 1:10-1:100; IP: 1:200-1:1000
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab00442(ANO2 antibody) at dilution of 1:500
IP Result of anti-ANO2 (IP:FNab00442, 4ug; Detection:FNab00442 1:300) with mouse brain tissue lysate 10000ug.
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab00442(ANO2 Antibody) at dilution of 1:50
- Background
- Calcium-activated chloride channel(CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors(OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina.
