Products
Amylin antibody
- Product Name
- Amylin antibody
- Catalogue No.
- FNab00384
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- islet amyloid polypeptide
- Alternative Names
- Amylin antibody, DAP antibody, Diabetes associated peptide antibody, IAP antibody, IAPP antibody, Insulinoma amyloid peptide antibody, islet amyloid polypeptide antibody
- UniProt ID
- P10997
- Observed MW
- 10 kDa
Application
- Tested Applications
- ELISA, IHC
- Recommended dilution
- IHC: 1:20-1:200
Validated Images
Immunohistochemistry of paraffin-embedded human pancreas tissue slide using FNab00384(Amylin Antibody) at dilution of 1:50?
- Background
- IAPP, also known as Amylin, is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. IAPP is co-secreted with insulin by pancreatic β-cells and largely contributes to glycemic control. Studies suggest that this protein, like the related beta-amyloid(Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
