Products
AMPK alpha 2 antibody
- Product Name
- AMPK alpha 2 antibody
- Catalogue No.
- FNab00376
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- protein kinase, AMP-activated, alpha 2 catalytic subunit
- Alternative Names
- AMPK antibody, AMPK alpha 2 antibody, AMPK subunit alpha 2 antibody, AMPK2 antibody, PRKAA antibody, PRKAA2 antibody
- UniProt ID
- P54646
- Observed MW
- 62 kDa
Application
- Tested Applications
- ELISA, WB, IF, IHC, IP
- Recommended dilution
- WB: 1:1000-1:10000; IHC: 1:20-1:200; IF: 1:10-1:100; IP:1:500-1:5000
Validated Images
human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab00376(PRKAA2 antibody) at dilution of 1:500
IP Result of anti-AMPK alpha 2 (IP:FNab00376, 4ug; Detection:FNab00376 1:1000) with mouse skeletal muscle tissue lysate 3600ug.
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue slide using FNab00376(PRKAA2 Antibody) at dilution of 1:50
- Background
- PRKAA2(protein kinase, AMP-activated, alpha 2 catalytic subunit), also named as AMPKA2, AMPK, PRKAA, AMPK2, belonogs to the CAMK Ser/Thr protein kinase family and SNF1 subfamily. PRKAA2 is an αβγ heterotrimer that is activated by low cellular energy status, such as decreases in both the ATP/AMP ratio and the phosphocreatine content and it is a glycogen synthase kinase, phosphorylating Ser7 at the NH2 terminus, which decreases glycogen synthase activity(PMID:14532170). The protein can be ubiquitinated(PMID:21224036).
