Products
Amphiphysin antibody
- Product Name
- Amphiphysin antibody
- Catalogue No.
- FNab00373
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- amphiphysin
- Alternative Names
- Amphiphysin antibody, AMPH1 antibody, AMPH antibody
- UniProt ID
- P49418
- Observed MW
- 120 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP
- Recommended dilution
- WB: 1:500-1:5000; IHC: 1:20-1:200; IP: 1:500-1:5000
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab00373(AMPH antibody) at dilution of 1:1000
IP Result of anti-Amphiphysin (IP:FNab00373, 4ug; Detection:FNab00373 1:1500) with mouse brain tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab00373(AMPH antibody) at dilution of 1:100
- Background
- Amphiphysin(AMPH), a synaptic vesicle-associated protein that is highly concentrated in nerve terminal, is an autoantigen of Stiff-Man syndrome with breast cancer. Amphiphysin contains a N-terminal BAR(Bin1/Amphiphysin/Rv167) domain followed by an endocytosis domain, and a C-terminal SH3 domain. Amphiphysin has been proposed to function as a linker between the clathrin coat and dynamin in the endocytosis of synaptic vesicles. It may also participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types.
