Products
Alpha galactosidase A antibody
- Product Name
- Alpha galactosidase A antibody
- Catalogue No.
- FNab00329
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- galactosidase, alpha
- Alternative Names
- Alpha galactosidase A antibody, galactosidase antibody, alpha antibody
- UniProt ID
- P06280
- Observed MW
- 49 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500-1:3000; IHC: 1:20-1:200; IF: 1:10-1:100
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00329(GLA antibody) at dilution of 1:1500
Immunohistochemistry of paraffin-embedded mouse kidney tissue slide using FNab00329(GLA Antibody) at dilution of 1:100
Immunofluorescence analysis of HeLa cells using FNab00329(GLA antibody) at dilution of 1:50. Blue: DAPI for nuclear staining.
- Background
- GLA, also named as Melibiase, Agalsidas and Alpha-galactosidase A, Belongs to the glycosyl hydrolase 27 family. It hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids. Fabry disease is an X-linked lysosomal storage disorder resulting from the deficient activity of GLA. Enzyme replacement therapy(ERT) with GLA is currently the most effective therapeutic strategy for patients with Fabry disease, a lysosomal storage disease.
