Products

anti- alpha 1 Antichymotrypsin / AACT antibody

FNab00318 Catalogue No.
Synonyms
A1 Antichymotrypsin, AACT, ACT, Alpha 1 antichymotrypsin, GIG24, GIG25, Serpin A3, SERPINA3
Host
Mouse
Reactivity
Human
Isotype
IgG2b
Tested Application
ELISA, WB, IHC
Product Information
Product Name
anti- alpha 1 Antichymotrypsin / AACT antibody
Catalogue No.
FNab00318
Size
100µg
Form
liquid
Purification
Protein A+G purification
Purity
≥95% as determined by SDS-PAGE
Host
Mouse
Clonality
monoclonal
Isotype
IgG2b
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Human SerpinA3, also known as Alpha 1-antichymotrypsin(AACT), is a member of the serine protease inhibitor class, and is a plasma alpha globulin glycoprotein which increases in the blood during the inflammatory process. SerpinA3, is also an inhibitor of neutrophil cathepsin G, mast cell chymases and pancreatic chymotrypsin. SerpinA3 is produced primarily in the liver, and is identified as an acute-phase inflammatory protein. SerpinA3 deficiency has been associated with liver disease. SerpinA3 has also been implicated in the pathology of a number of devastating human diseases including chronic obstructive pulmonary disease(COPD), Parkinson’s disease(PD), Alzheimer’s disease(AD), Stroke, Cystic Fibrosis, Cerebral Haemorrhage and Multiple System Atrophy.
Immunogen Information
Immunogen
serpin peptidase inhibitor, clade A(alpha-1 antiproteinase, antitrypsin), member 3
Synonyms
A1 Antichymotrypsin, AACT, ACT, Alpha 1 antichymotrypsin, GIG24, GIG25, Serpin A3, SERPINA3
Observed MW
60 kDa
Application
Tested Application
ELISA, WB, IHC
Recommended dilution
WB: 1:1000-1:10000; IHC: 1:20-1:300
Uniprot information
UniProt ID
P01011
Images
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab00318(AACT antibody) at dilution of 1:200
human blood tissue were subjected to SDS PAGE followed by western blot with FNab00318(AACT antibody) at dilution of 1:5000