Products
AKNA antibody
- Product Name
- AKNA antibody
- Catalogue No.
- FNab00259
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- AT-hook transcription factor
- Alternative Names
- AKNA antibody, AT hook transcription factor antibody, FLJ31001 antibody, FLJ33184 antibody, KIAA1968 antibody, RP11 82I1.4 antibody
- UniProt ID
- Q7Z591
- Observed MW
- 65-70 kDa
Application
- Tested Applications
- ELISA, IHC, WB
- Recommended dilution
- WB: 1:200-1:2000; IHC: 1:20-200
Validated Images
Raji cells were subjected to SDS PAGE followed by western blot with FNab00259(AKNA Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab00259(AKNA Antibody) at dilution of 1:50
- Background
- AKNA also named as AT hook transcription factor is a 1439 amino-acids protein. AKNA, encodes a lymphoid-specific AT-hook transcription factor that is highly expressed by B and T lymphocytes. It coordinately regulates expression of the CD40 receptor and its ligand (CD154), two molecules that are critical for antigen-dependent B-cell development. AKNA expresses at least nine distinct transcripts, some of which are expressed in a tissue-specific manner. These transcripts are products of alternative splicing, alternative promoter usage, and alternative polyadenylation. The alternative AKNA transcripts are predicted to encode overlapping protein isoforms, some of which (p70 and p100) (PMID:15869410)
