Immunohistochemical of paraffin-embedded human pancreas cancer using FNab00223(AGTRAP antibody) at dilution of 1:10
Background
Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity.