Products

ADRP antibody

Synonyms:ADFP antibody, Adipophilin antibody, ADRP antibody, Perilipin 2 antibody, PLIN2 antibody
Catalogue No.:FNab00183Reativity:Human
Host:MouseTested Application:ELISA, WB, IHC
Clonality:monoclonalIsotype:IgG1
  • SPECIFICATIONS
Product Name
ADRP antibody
Catalogue No.
FNab00183
Size
100μg
Form
liquid
Purification
Protein A+G purification
Purity
≥95% as determined by SDS-PAGE
Clonality
monoclonal
Isotype
IgG1
Clone ID
1G4
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
adipose differentiation-related protein
Alternative Names
ADFP antibody, Adipophilin antibody, ADRP antibody, Perilipin 2 antibody, PLIN2 antibody
UniProt ID
Q99541
Observed MW
50 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:50-1:500
Validated Images
human adipose tissue were subjected to SDS PAGE followed by western blot with FNab00183(ADRP Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human renal cell carcinoma tissue slide using FNab00183( ADRP Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Background
ADRP(adipocyte differentiation related protein) also known as ADFP, adipophilin, or perilipin-2, is a member of PAT family which is responsible for the transportation of lipids and the formation of lipid droplets. ADRP is localized on the surface of lipid droplets in a variety of tissues and cell lines. ADRP is not detected in undifferentiated cells but increases rapidly to high levels when adipocyte precursors differentiate into adipocytes. Anti-ADRP antibody is a reliable and sensitive marker for lipid droplet. Enhanced expression of ADRP is linked to diseases with abnormal lipid storage, including hepatic steatosis, atherosclerosis and diabetes. Immunohistochemistry of ADRP may facilitate histomorphological diagnosis of these diseases.