L02 cells were subjected to SDS PAGE followed by western blot with FNab00171(ADIPOR2 antibody) at dilution of 1:500
IP Result of anti-ADIPOR2 (IP: FNab00171, 4ug; Detection: FNab00171 1:500) with HeLa cells lysate 2800ug.
Background
Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism(PubMed:12802337, PubMed:25855295). Required for normal body fat and glucose homeostasis. ADIPOQ-binding activates a signaling cascade that leads to increased PPARA activity, and ultimately to increased fatty acid oxidation and glucose uptake. Has intermediate affinity for globular and full-length adiponectin. Required for normal revascularization after chronic ischemia caused by severing of blood vessels(By similarity).