Products
ACVRL1 antibody
- Product Name
- ACVRL1 antibody
- Catalogue No.
- FNab00131
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- activin A receptor type II-like 1
- Alternative Names
- Activin receptor like kinase 1 antibody, ACVRL1 antibody, ACVRLK1 antibody, ALK 1 antibody, ALK1 antibody, HHT antibody, HHT2 antibody, ORW2 antibody, SKR3 antibody, TSR I antibody
- UniProt ID
- P37023
- Observed MW
- 56 kDa
Application
- Tested Applications
- ELISA, WB, IHC, FC, IP
- Recommended dilution
- WB: 1:200-1:1000; IHC: 1:100-1:400; IP: 1:200-1:1000
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab00131(ACVRL1 antibody) at dilution of 1:400
IP Result of anti-ACVRL1 (IP:FNab00131, 4ug; Detection:FNab00131 1:300) with Jurkat cells lysate 2400ug.
Immunohistochemistry of paraffin-embedded human heart tissue slide using FNab00131(ACVRL1 Antibody) at dilution of 1:200
- Background
- Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.
