Products
ACADVL antibody
- Product Name
- ACADVL antibody
- Catalogue No.
- FNab00068
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- acyl-Coenzyme A dehydrogenase, very long chain
- Alternative Names
- ACAD6 antibody, ACADVL antibody, LCACD antibody, VLCAD antibody
- UniProt ID
- P49748
- Observed MW
- 48 kDa,68-73 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:200-1:2000; IHC: 1:20-1:200
Validated Images
Various lysates were subjected to SDS PAGE followed by western blot with FNab00068(ACADVL antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver cancer using FNab00068(ACADVL antibody) at dilution of 1:50
- Background
- Very long-chain acyl-CoA dehydrogenase (VLCAD) is one of four flavoproteins which catalyze the initial step of the mitochondrial b-oxidation spiral. It belongs to the acyl-CoA dehydrogenase family and is a homodimer of a 71-kDa polypeptide. The molecular mass of the nondenatured trypsinized VLCAD is 98 kDa, by gel filtration chromatography, indicating that it is a homodimer of the 48 kDa(tryptic digest) polypeptide(PMID:9461620). Defects in ACADVL are the cause of acyl-CoA dehydrogenase very long chain deficiency (ACADVLD). It has 2 isoforms(70 kDa and 68 kDa ) produced by alternative splicing and a transit peptide.
