Products
ABHD2 antibody
- Product Name
- ABHD2 antibody
- Catalogue No.
- FNab00049
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- abhydrolase domain containing 2
- Alternative Names
- ABHD2 antibody, Protein PHPS1 2 antibody, HS1 2 antibody, Lung alpha/beta hydrolase 2 antibody, LABH2 antibody
- UniProt ID
- P08910
- Observed MW
- 48 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:5000; IHC: 1:20-1:200
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00049(ABHD2 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human spleen using FNab00049(ABHD2 antibody) at dilution of 1:100
- Background
- Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol(AG) from cell membrane(PubMed:26989199). Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol(1AG) and 2-arachidonoylglycerol(2AG) to glycerol and arachidonic acid(AA)(PubMed:26989199). Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation(PubMed:26989199). May also play a role in smooth muscle cells migration(By similarity).
