Products
ABCE1 antibody
- Product Name
- ABCE1 antibody
- Catalogue No.
- FNab00039
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ATP-binding cassette, sub-family E(OABP), member 1
- Alternative Names
- ABCE1 antibody, RLI antibody, RNase L inhibitor antibody, RNASEL1 antibody, OABP antibody
- UniProt ID
- P61221
- Observed MW
- 67 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:2000
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00039(ABCE1 antibody) at dilution of 1:1500
- Background
- Antagonizes the binding of 2-5A(5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly.
