Products
5 Lipoxygenase antibody
- Product Name
- 5 Lipoxygenase antibody
- Catalogue No.
- FNab00007
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- arachidonate 5-lipoxygenase
- Alternative Names
- 5 Lipoxygenase antibody, 5 LO antibody, 5 LOX antibody, 5LPG antibody, ALOX5 antibody, LOG5 antibody
- UniProt ID
- P09917
- Observed MW
- 68-78 kDa
Application
- Tested Applications
- ELISA, IF, WB
- Recommended dilution
- WB: 1:200-1:2000; IF: 1:20-1:100
Validated Images
HL-60 cells were subjected to SDS PAGE followed by western blot with FNab00007(ALOX5 Antibody) at dilution of 1:600
- Background
- ALOX5(arachidonate 5-lipoxygenase) is also named as LOG5, 5-LO and belongs to the lipoxygenase family. It catalyzes the first step in leukotriene biosynthesis, and plays a role in inflammatory processes. It is a 78 kDa iron-containing enzyme that translocates from the cytosol to associate with FLAP, and converts arachidonate in two steps into the unstable intermediate LTA4. It is essential for cysteinyl-leukotriene(cys-LT) production, critical mediators in asthma(PMID:12911785).
