DSS Blocker Diluent

E145

100mL

The kit should be stored at 2-8℃ for 12 months.

Dextran sulfates (DSS) are anionic polymers produced by the reaction of dextran with chlorosulfuric acid, with a sulfur content of approximately 17% (equivalent to an average of 1.9 sulfate groups per glucose residue). In studies on inflammatory bowel disease (IBD) and colorectal cancer, DSS with molecular weights of 36,000–50,000 Da induces colitis in mice and rats by binding to chain fatty acids in the colon and triggering inflammation. DSS is a water-soluble polyanionic complex that forms a clear, colorless solution. It is commonly administered at 2%–5% directly in the drinking water of animals to establish disease models, or used at 3% in serum-free culture medium to stimulate cells to secrete inflammatory cytokines such as IL-6 and IL-10. However, when samples containing more than 0.3% DSS are used in ELISA assays, significant high background signals may occur, affecting data analysis. FineTest has developed a specialized blocking sample diluent (DSS Blocker Diluent) for high-concentration DSS samples, which effectively reduces background and restores assay accuracy.

1. This kit is for research use only. If used for clinical diagnosis or any other purposes, our company shall not be liable for any problems arising therefrom, nor assume any legal responsibility.

2. Please read the instructions carefully before the experiment and calibrate all instruments accordingly. Strictly follow the instructions throughout the procedure.

3. During the experiment, please wear laboratory coats and latex gloves to ensure proper protection.

4. The final experimental results are closely related to factors such as the validity of the reagents, the operator's technique, and the experimental environment. Our company is only responsible for the product itself and assumes no responsibility for sample consumption resulting from the use of the product. Please fully consider the potential sample usage and reserve sufficient samples before use.