NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab10006(Phospho- MTOR(S2448) antibody) at dilution of 1:1000
Background
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.