Mouse kidney were subjected to SDS PAGE followed by western blot with FNab09967(CLDN5 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse kidney using FNab09967(GLDN5 antibody) at dilution of 1:100
Background
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene.