Products
MAGEA6 antibody
- Product Name
- MAGEA6 antibody
- Catalogue No.
- FNab04939
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- melanoma antigen family A, 6
- Alternative Names
- Melanoma-associated antigen 6|Cancer/testis antigen 1.6 (CT1.6)|MAGE-6 antigen|MAGE3B antigen|MAGEA6|MAGE6 antibody
- UniProt ID
- P43360
- Observed MW
- 66-70 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab04939(MAGEA6 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human lung cancer using FNab04939(MAGEA6 antibody) at dilution of 1:50
- Background
- Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme(E2) at the E3:substrate complex. May play a role in tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines.
