L02 cells were subjected to SDS PAGE followed by western blot with FNab03884(HIST1H1C antibody) at dilution of 1:500
Background
Histone H1 regulates chromatin competency through its high affinity binding to linker DNA as a structural component. It acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation. The calcualted molecular weight of Histone H1.2 is 21 kDaa, but modified Histone H1.2 is about 32 kDaa.