HepG2 cells were subjected to SDS PAGE followed by western blot with FNab01333(CBX6 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human skin slide using FNab01333(CBX6 Antibody) at dilution of 1:50
Background
Component of a Polycomb group(PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.