SH-SY5Y cells were subjected to SDS PAGE followed by western blot with FNab00485( APLNR antibody at dilution of 1:600
Immunohistochemistry of paraffin-embedded human colon tissue slide using FNab00485(anti- APLNR antibody) at dilution of 1:50
Background
Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for APELA hormone. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.